One of the key areas of AFAO’s work is the development and national implementation of HIV and STI prevention and health promotion programs and resources. The purpose of AFAO's health promotion is to strengthen populations, communities and individuals so that they can enjoy health, well-being and a good quality of life as a way for achieving their potential in other parts of their lives.
AFAO's Policy and Communications team provides policy advice on HIV-related issues, and undertakes policy analysis and law reform advocacy regarding Australia's response to HIV.
Internationally they contribute to the development of effective policy and programmatic responses to HIV/AIDS at the global level, particularly in the Asia Pacific region.
AFAO's members are the AIDS councils in each state and territory, the National Association of People Living with HIV/AIDS (NAPWA), the Australian Injecting & Illicit Drug Users League (AIVL), the Anwernekenhe National Aboriginal and Torres Strait Islander HIV/AIDS Alliance (ANA), and Scarlet Alliance, the Australian Sex Workers Association.