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Haemolytic uraemic syndrome (HUS)

6-minute read

Go to the emergency department if you or your child is passing very little urine (wee) or has unusual bleeding or bruises after having bloody diarrhoea and stomach pain.

Key facts

  • Haemolytic uraemic syndrome (HUS) is a rare, life-threatening illness where your kidneys stop working properly.
  • HUS is most common in children younger than 5 years of age.
  • HUS is most commonly caused by an infection from a type of E.coli bacteria.
  • If you have HUS, you will need treatment in hospital.

What is HUS?

Haemolytic uraemic syndrome (HUS) is a rare but serious illness that can be life-threatening and is caused by a bacterial infection. HUS causes inflammation and the blood vessels to clot in the kidneys. This prevents the kidneys from working properly. HUS also causes changes to your blood, including anaemia and low platelet count.

You can get HUS at any age but it’s most common in children under the age of 5 years. Young children and older adults are at greater risk of severe disease.

What are the symptoms of HUS?

Your early symptoms depend on the cause of your HUS.

The most common cause of HUS is an infection from a type of E.coli bacteria. Your first symptoms may include about 5 to 10 days of:

Whatever causes your HUS, later symptoms can include:

CHECK YOUR SYMPTOMS — Use the Symptom Checker and find out if you need to seek medical help.

What causes HUS?

The most common cause of HUS is a type of bacterium called Shiga toxin-producing E.coli (STEC). It is commonly found in cow and sheep faeces (poo).

You can catch STEC if you:

  • eat undercooked meat
  • drink unpasteurised (‘raw’) milk or juice
  • drink or swim in contaminated water
  • touch cows and sheep, or their faeces, then put your hand in your mouth
  • eat unwashed vegetables that were in contact with animal faeces

You can also catch STEC through close contact with someone who has the infection or with surfaces they’ve touched, such as toys, nappies, taps or toilet flushes. The STEC bacterium produces toxins (poisonous substances) that damage your digestive tract (gut) and can cause HUS. This happens in a small number of the people infected with the bacterium, but most people infected with STEC don’t develop HUS.

Other less common causes of HUS include other infections and medicines (such as some drugs for cancer, autoimmune diseases and a complication of pregnancy).

When should I see my doctor?

HUS is a serious disease and if you have symptoms, see a doctor immediately.

HUS is a notifiable disease. This means that your doctor must tell the Australian Government’s Department of Health and Aged Care if you’re diagnosed with HUS. The Department needs to monitor and track all cases of HUS to find outbreaks and improve healthcare responses.

FIND A HEALTH SERVICE — The Service Finder can help you find doctors, pharmacies, hospitals and other health services.

How is HUS diagnosed?

If your doctor thinks that you have HUS, they will ask about your symptoms and examine you. Blood, urine and stool tests can help them make a diagnosis.

ASK YOUR DOCTOR — Preparing for an appointment? Use the Question Builder for general tips on what to ask your GP or specialist.

How is HUS treated?

If you have HUS, you may need intensive care in hospital, generally for about 1 to 2 weeks. You may need intravenous fluids (IV) and a blood transfusion. If your kidneys aren’t working properly, you may need dialysis.

Can HUS be prevented?

You can reduce the chance that you and your children get HUS by taking care to eat properly cooked and washed foods, washing your hands often (including before eating), avoiding unpasteurised milk (also known as raw milk) and juices, and only drinking treated water (such as Australian tap water and other chemically treated water, boiled water or purified water).

What are the complications of HUS?

Long-term complications of HUS can include kidney failure, high blood pressure and seizures. If you have not passed urine for around 10 to 14 days, or need a long period of dialysis, you have a greater risk of long-term kidney problems.

Resources and support

  • To find out more about haemolytic uraemic syndrome, or to get advice on what to do next, speak with your doctor. You can also call healthdirect on 1800 022 222 to speak with a registered nurse, 24 hours, 7 days a week (known as NURSE-ON-CALL in Victoria).
  • Find out more about haemolytic uraemic syndrome from the Australian Government Department of Health and Aged Care.
  • Learn about the rare atypical form of haemolytic uraemic syndrome (aHUS) from Genetic Alliance Australia.

Learn more here about the development and quality assurance of healthdirect content.

Last reviewed: March 2023

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Haemolytic uraemic syndrome (HUS) | SA Health

Infection with Shiga Toxin Producing Escherichia coli (STEC) may cause haemolytic uraemic syndrome (HUS) with serious consequences

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Haemolytic uraemic syndrome - Better Health Channel

Haemolytic uraemic syndrome (HUS) is a rare condition which can lead to chronic kidney damage or death from kidney failure.

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Haemolytic Uraemic Syndrome (HUS) fact sheet - Fact sheets

STEC (also known as VTEC) infection can cause serious disease, including bloody diarrhoea, and sometimes haemolytic uraemic syndrome.

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Haemolytic uraemic syndrome (HUS) | Australian Government Department of Health and Aged Care

Find out how we define and monitor cases of HUS, and where you can learn more about this disease.

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List of nationally notifiable diseases | Australian Government Department of Health and Aged Care

This page lists diseases that states and territories have agreed to report to us through the National Notifiable Diseases Surveillance System.

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Shiga toxin-producing E.coli - Better Health Channel

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List of notifiable conditions | Queensland Health

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