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Endone is a pain relief medicine.

Endone is a pain relief medicine.
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Endone side effects and addiction

3-minute read

Endone is the brand name of a pain relief medication that contains the active ingredient oxycodone hydrochloride. It belongs to a group of pain medicines called narcotic analgesics.

Endone side effects

Endone has many possible side effects. The more common side effects include:

It’s important to tell your doctor as soon as possible if you notice any other symptoms after taking Endone, as some can indicate serious complications. Go to the NPS MedicineWise website for lists of Endone side effects.

Endone overdose

If you take too much Endone (known as an overdose), it’s important to get immediate medical attention because it can cause respiratory failure, cardiac arrest or death.

Symptoms of overdose include feeling sleepy and/or difficulty in breathing which could lead to unconsciousness and loss of muscle control.

If you are concerned about an overdose of Endone (or other brand of oxycodone) contact the Poisons Information Centre on 13 11 26 for advice.

Access to overdose-reversing medication

Naloxone is a drug that can reverse the effects of an opioid overdose. A pilot program, funded by the Australian government, will offer certain individuals in NSW, SA and WA this medication (including the nasal spray Nyxoid) for free and without a prescription during the period 1 December 2019 to 28 February 2021.

Learn more about the Take Home Naloxone pilot here, or contact the Pharmacy Programs Administrator to find out how to register.

Endone addiction

Endone is from the same family of drugs as heroin, and like heroin it can be addictive.

People who take a lot of Endone for long periods can find their body adapts to having regular Endone. As well as becoming less effective if the regular dose is not taken, they go into withdrawal. This makes cutting down or stopping Endone difficult.

They may also find that their thoughts and emotions focus on the drug, that they have strong urges to use the drug, and that they continue to use it despite it causing difficulties in their lives.

  • need to use the drug in larger amounts or for longer than intended
  • have unpleasant effects when stopping the drug (withdrawal)
  • have a constant urge to use the drug and find it hard to control or reduce use
  • spend a great deal of time in drug-related behaviour (obtaining, taking, recovering)
  • give up other important parts of life to use it
  • continue to use it even though it's associated with problems, including health, family, work, or financial difficulties

Common withdrawal symptoms include:

  • rebound pain or increased pain sensitivity
  • restlessness and agitation
  • inability to sleep
  • gastrointestinal problems
  • excessive sweating
  • feeling cold and shivering

Treating Endone and other opioid dependence can require many attempts and a great deal of support. It’s a good idea to seek professional help from your doctor and you may need referral to an addiction specialist.

Learn more here about the development and quality assurance of healthdirect content.

Last reviewed: October 2018

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