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Endone is a pain relief medicine.

Endone is a pain relief medicine.
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3-minute read

What is Endone?

Endone is a painkiller. It's the brand name of a medicine containing the active ingredient oxycodone hydrochloride. Other brands of oxycodone include OxyContin and OxyNorm. It comes in different dosages and forms such as tablets, capsules, suppositories and liquid.

Endone is a narcotic, like morphine, heroin and codeine. It should be used to relieve moderate or severe pain, such as after surgery or an injury.

Is it safe to take Endone?

Endone needs to be prescribed by a doctor who will specify its use in a safe and effective manner based on an assessment of your condition. Endone can cause drowsiness, sleepiness or dizziness in some people, so your doctor may recommend avoiding driving or operating machinery until you know how it affects you.

Endone can interact with alcohol and your doctor may advise you to avoid alcohol while you are taking it.

Endone has many potential interactions with other drugs. It’s important to tell your doctor about all the medicines you are taking, including non-prescription medicines that you may buy from pharmacies, health food stores or supermarkets.

It’s also important to tell your doctor if you have any allergies or if you are pregnant or breastfeeding.

Be careful not to accidentally double dose by taking different brands (such as OxyContin and OxyNorm) with the same active ingredient. Do not take a double dose to make up for a dose that you have missed.

Access to overdose-reversing medication

Naloxone is a drug that can reverse the effects of an opioid overdose. A pilot program, funded by the Australian government, will offer certain individuals in NSW, SA and WA this medication (including the nasal spray Nyxoid) for free and without a prescription during the period 1 December 2019 to 28 February 2021.

Learn more about the Take Home Naloxone pilot here, or contact the Pharmacy Programs Administrator to find out how to register.

How do I take Endone?

It’s important to follow the directions given to you by your doctor or pharmacist. Endone is taken with a full glass of water, after meals or with milk. The usual dose depends on the direction of the prescribing doctor and usually can be up to one tablet every 6 hours.

If you have been taking Endone for more than a short while it’s also important not to suddenly stop taking the medication but to gradually reduce the amount you are taking, under the direction of your doctor. This will help to reduce the risk of withdrawal symptoms occurring.

See healthdirect's medicines section for more information about Endone.

Learn more here about the development and quality assurance of healthdirect content.

Last reviewed: October 2018

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