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Active ingredient: clozapine

The medicines below all contain the following active ingredient(s): clozapine. You can select a medicine from this list to find out more - including side effects, age restrictions, food interactions and whether the medicine is subsidised by the government on the pharmaceutical benefits scheme (PBS).

Safety advice: constipation - a potentially serious side effect

Product Information (PI) and Consumer Medicine Information (CMI) for clozapine have been updated to strengthen warnings about potential severe gastrointestinal side effects, including constipation.

Clozapine is used to treat schizophrenia when other antipsychotic medicines either have not worked or have caused severe side effects. In Australia it is known by the brand names Clozaril, Clopine and others.

Information for consumers

If you or someone you provide care for is taking clozapine, you should contact a health professional immediately if constipation develops or there are any signs that bowel activity is slowing down.

More information: For more details and the latest updates, see TGA's alert on Clozapine.

Medicines that contain clozapine

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