Physeptone™

Read the CMI leaflet (Opens in new tab) for facts you need to know before, during and after taking your medicine.

For more information about CMIs and how to read them, please visit How to read Consumer Medicine Information (CMI).

PHYSEPTONE is indicated for the management of severe pain where: (i) other treatment options have failed, are contraindicated, not tolerated or are otherwise inappropriate to provide sufficient management of pain, and (ii) the pain is opioid-responsive, and (iii) requires daily, continuous, long-term treatment. ,PHYSEPTONE is not indicated for use in chronic non-cancer pain other than in exceptional circumstances.,PHYSEPTONE is not indicated as an as-needed (PRN) analgesia.,PHYSEPTONE is not recommended for use in ambulant patients.

Source: ARTG

• Shelf lifetime is 36 Months
• Store below 25 degrees Celsius
• Protect from Light; Store in a Dry Place

Source: ARTG

Non-composite pack

This medicine contains one component only.

Component

• Tablet, uncoated
• Oral
• White biconvex scored tablet on one side and plain on the other

Source: ARTG

These medicines require authorisation for prescription from your doctor. It is Schedule 8: Controlled Drug.?What is the medicines and poisons schedule?

All medicines and poisons in Australia are categorised by how they are made available to the public. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk. This system is called ‘scheduling’. You can read more about the scheduling of medicines as well as the different scheduling categories on our Scheduling of medicines and poisons information page.

• 20 tablets

Source: ARTG

This medicine was verified as available on the Pharmaceutical Benefits Scheme (PBS) on 1 November 2026, under PBS item codes 1609Q (Opens in new tab) and 12520Y (Opens in new tab). Ask your pharmacist or doctor about your eligibility

Source: PBS

For the active ingredient: Methadone

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Source: AHT

If you experience a side effect from this medicine, tell your doctor or pharmacist. Or report it directly to the TGA (Therapeutic Goods Administration).

You can report side effects to your doctor, or directly at Report an adverse event or safety problem (Opens in new tab)

Source: ARTG

Healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.

Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions (Opens in new tab).