Healthdirect Free Australian health advice you can count on.

Medical problem? Call 1800 022 222. If you need urgent medical help, call triple zero immediately

healthdirect Australia is a free service where you can talk to a nurse or doctor who can help you know what to do.

beginning of content


7-minute read

Key facts

  • Chemotherapy uses strong medicines to destroy cancer cells.
  • Chemotherapy can be used by itself to treat cancer, or together with other types of treatment, such as surgery and radiotherapy.
  • Chemotherapy may also damage healthy cells causing a range of side effects which can often be managed with medicines and other strategies suggested by your medical team.
  • The type, dose and length of chemotherapy recommended will depend on the type and stage of cancer, your general health and your treatment goals.

What is chemotherapy?

Chemotherapy is a word used to describe a group of strong medicines often used to treat cancer. Chemotherapy is used to destroy cells that grow quickly — including cancer cells, which are usually fast-growing.

How does chemotherapy work?

Your body is made up of billions of small building blocks called cells. The different tissues and organs of your body are comprised of different types of cells. Your body’s cells reproduce to make new cells. When you are healthy, this process of division is tightly controlled and only takes place when needed, for example, to replace damaged or old cells. If your cells begin to grow and divide in an uncontrolled way, you may develop a cancer.

Chemotherapy is designed to target cells that grow quickly, such as cancer cells. Chemotherapy is known as a ‘cytotoxic’ medication — this means that it is poisonous (‘toxic’) to cells (‘cyto’ means ‘cell’).

Chemotherapy may be used in cancer treatment for a few different reasons:

  • Curative chemotherapy is designed to directly treat the cancer and try to destroy it, usually without the use of other treatments.
  • Neoadjuvant chemotherapy is used before surgery to remove a cancerous tumour, to try and shrink it to make it easier to remove during surgery.
  • Adjuvant chemotherapy is used together with other treatments such as surgery and radiotherapy to increase the chance of successfully destroying the cancer.
  • Palliative chemotherapy is not usually meant to cure cancer. It can be used to reduce cancer size, which can improve symptoms caused by a cancerous tumour or to limit the growth and spread of the cancer and prolong life. This kind of chemotherapy may be used for months or years.

How is chemotherapy given?

Chemotherapy can be given in a few different ways, depending on the type of cancer and how far it has spread.

Chemotherapy is often given directly into your blood through a vein (intravenously, or IV). If this is the case, it will often be given at a day hospital or day-treatment centre and you can usually go home between sessions. Sessions may last for anywhere between less than an hour and several hours, depending on the kind of chemotherapy you are getting and how you feel during and after treatment.

If the medicine needs to be given for only a short time (up to a few days), it can be given through a small plastic tube (cannula) inserted into a vein, usually in your hand or arm. It is placed with the help of a small needle in a procedure that is much like how a blood test is performed.

If you need to receive IV treatment for a longer period of time, your doctor or oncologist may discuss adminitstering a ‘port’. This kind of intravenous tube which can stay in place for weeks or months, saving you from getting a new IV line every time you receive chemotherapy.

Chemotherapy can also be given in other ways, for example in the form of tablets or a cream. It can also be injected into a specific body area for certain types of cancer.

What are the side effects of chemotherapy?

Chemotherapy uses strong medicines which often have side effects. Everyone responds differently to chemotherapy; you may experience many or few of these side effects and feel them strongly or only mildly.

Most commonly, people on chemotherapy feel tired and fatigued. As chemotherapy affects fast-growing cells, it commonly causes side effects in your skin, hair, gut and immune system, since the cells in these areas are particularly fast-growing.

These side effects can include:

Some chemotherapy medicines can have a higher chance of damaging specific areas of your body, such as your heart, lungs, bladder or nervous system. These effects may last temporarily or permanently. Ask your doctor about the medicines recommended for you and any specific effects that they may have on your body.

There are many medicines and strategies which can help ease any side effects that you may experience. For example, your doctor can prescribe medicines to help with nausea. Ice chips can help sooth a sore mouth, and there are even treatments such as ‘cold caps,’ which can help reduce hair loss. Your medical team can give you more detailed suggestions and advice about what is available to help you remain as comfortable as possible during your treatment.

How long will I need chemotherapy?

The specific type, dose and length of your chemotherapy will depend on many factors, including the type and stage of your cancer, your general health, the purpose of the chemotherapy and how well your cancer is responding to treatment.

Chemotherapy is usually given in ‘cycles’. For example, a patient may receive 2 weeks of treatment then have a 2-week break, before this cycle continues. This gives your body a chance to recover and you and your medical team a chance to see how well your cancer responds to the treatment. You may need blood tests or scans between treatment cycles to check on the cancer, and to make sure your body has recovered enough to cope with the next dose of chemotherapy. Your medical team may make changes to your treatment based on how you feel and on your test results.

Will chemotherapy affect my fertility?

In both men and women, chemotherapy can affect your fertility by damaging the cells of your reproductive organs, such as eggs or sperm. Sometimes these cells will recover months or years after chemotherapy, but sometimes the damage is permanent.

In women, chemotherapy may also affect your menstrual cycle, causing it to become irregular or stop completely while you are receiving treatment. In some cases, your cycle will return after you stop chemotherapy, but in other cases it will stop permanently, causing early menopause, and making it impossible to conceive naturally.

Some people choose to take steps to preserve their fertility before starting cancer treatment. These steps can include freezing eggs, sperm or embryos, or involve more complex treatments.

Your options will depend on the cancer you have and on the treatment suggested by your doctor. You may wish to discuss fertility preservation with your medical team before you start any cancer treatments.

Despite this, it is important to realise that you may still be fertile while undergoing cancer treatment. Chemotherapy is considered dangerous for an unborn baby, who has many fast-growing cells, so you may also wish to discuss contraception with your doctor before starting treatment.

Resources and support

Dealing with cancer and cancer treatment can feel very overwhelming. There are many organisations that can help with information and support, including:

Learn more here about the development and quality assurance of healthdirect content.

Last reviewed: May 2021

Back To Top

Need more information?

These trusted information partners have more on this topic.

Top results

Chemotherapy | Cancer Council

What is chemotherapy? Find credible information on chemotherapy, including its side effects, how and why it's used, how it's given and more

Read more on Cancer Council Australia website

Chemotherapy: Overview - Cancer Council Victoria

Understand more about chemotherapy, one of the main treatments for cancer, including what it is, how it works, how long treatment lasts, how to prepare and more key questions.

Read more on Cancer Council Victoria website

Bone cancer - Better Health Channel

Bone cancer is a rare form of cancer that is treated with chemotherapy, radiotherapy or hormone therapy.

Read more on Better Health Channel website

Treatment options for cancer | NT.GOV.AU

Surgery, chemotherapy, radiotherapy, hormone therapy, steroid therapy, transplants and alternative treatments for cancer.

Read more on NT Health website

What is neutropenia? | Cancer Council

Neutropenia can come on suddenly, been there for a long time or come and go. Find out more about neutropenia and how it can be a chemotherapy side effect

Read more on Cancer Council Australia website

Cancer Treatments - Cancer Council Victoria

Learn about different types of cancer treatment, including chemotherapy, radiation therapy, surgery and more.

Read more on Cancer Council Victoria website

Cancer | Lifeblood

If you have cancer, you might need a transfusion for a number of reasons, including an operation, side effects of chemotherapy, and as a result of the actual cancer.

Read more on Australian Red Cross Lifeblood website

Cancer treatment - Australian Dental Association

Treatments for cancer, including chemotherapy and radiation therapy, can lead to side effects in the mouth. Side effects can include mouth soreness and mouth ulcers (oral mucositis), a dry mouth, and a change in the ability to taste.

Read more on website

Acute promyelocytic leukaemia treatment - Leukaemia Foundation

Acute promyelocytic leukaemia treatment Listen How is APML treated? The treatment for APML differs from the treatment of other types of acute leukaemia because it involves the use of a “retinoid” drug, which is not a chemotherapy drug; it is actually a derivative of vitamin A, which works by making the immature promyelocytes (the identifiable leukaemic cells in APML) mature properly

Read more on Leukaemia Foundation website

Nerve pain and numbness: overview - Cancer Council Victoria

Sometimes cancer can damage the peripheral nerves, causing pain or numbness.

Read more on Cancer Council Victoria website

Healthdirect 24hr 7 days a week hotline

24 hour health advice you can count on

1800 022 222

Government Accredited with over 140 information partners

We are a government-funded service, providing quality, approved health information and advice

Australian Government, health department logo ACT Government logo New South Wales government, health department logo Northen Territory Government logo Government of South Australia, health department logo Tasmanian government logo Victorian government logo Government of Western Australia, health department logo

Healthdirect Australia acknowledges the Traditional Owners of Country throughout Australia and their continuing connection to land, sea and community. We pay our respects to the Traditional Owners and to Elders both past and present.