Closina™
Active ingredients: Cycloserine
Pack: Closina 250 mg capsule, 100, bottle
Consumer medicine information
For more information about CMIs and how to read them, please visit How to read Consumer Medicine Information (CMI).
What this medicine is used for
Cycloserine is indicated in the treatment of active pulmonary and extra-pulmonary tuberculosis (including renal disease) when the organisms are susceptible to this drug and after failure of adequate treatment with the primary medications (streptomycin, isoniazid, rifampicin and ethambutol). Like all anti-tuberculous drugs, cycloserine should be administered in conjunction with other effective chemotherapy and not as the sole therapeutic agent. Cycloserine may be effective in the treatment of acute urinary tract infections caused by susceptible strains of Gram-positive and Gram negative bacteria, especially Klebsiella/Enterobacter species and Escherichia coli. It is generally no more and may be less effective than other antimicrobial agents in the treatment of urinary tract infections should be considered only when the more conventional therapy has failed and when the organism has been demonstrated to be sensitive to the drug.
Source: ARTG
Storage conditions
- Shelf lifetime is 1 Years
- Store below 25 degrees Celsius
Source: ARTG
How to use this medicine
Non-composite pack
This medicine contains one component only.
Component
- Capsule, hard
- Oral
- Size 1 gelatin capsules, opaque red cap, opaque grey body, printed "Lilly F04" in black ink
Source: ARTG
Do I need a prescription?
These medicine packs are available from a pharmacist and requires a prescription. It is Schedule 4: Prescription Only Medicine.
- 100
Source: ARTG
Is this medicine subsidised?
This medicine is not listed on the Pharmaceutical Benefits Scheme (PBS). Talk to your pharmacist about how much it will cost.
Source: PBS
Pregnant or planning a pregnancy?
For the active ingredient: Cycloserine
You should seek advice from your doctor or pharmacist before taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.
Source: AHT
Reporting side effects
If you experience a side effect from this medicine, tell your doctor or pharmacist. Or report it directly to the TGA (Therapeutic Goods Administration).
You can report side effects to your doctor, or directly at Report an adverse event or safety problem (Opens in new tab)
Source: ARTG
Data sources
- Australian Health Thesaurus (AHT) (Opens in new tab) – Last updated on 1 October 2026
- Australian Medicines Terminology (AMT) (Opens in new tab) – Last updated on 1 October 2026
- Australian Register of Therapeutic Goods (ARTG) (Opens in new tab) – Last updated on 1 October 2026
- Pharmaceutical Benefits Scheme (PBS) (Opens in new tab) – Last updated on 1 October 2026
- Medicines Information Pty Ltd (Opens in new tab) – Last updated on 4 March 2026
Disclaimer
Healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.
Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions (Opens in new tab).
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