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Brand name: D3 Drops Forte (Bioceuticals) TM

Active ingredients: colecalciferol

What it is used for

[1] The working group of the Australian and New Zealand Bone and Mineral Society, Endocrine Society of Australia and Osteoporosis Australia state that a significant number of Australians are deficient in vitamin D. [2] Vitamin D3 is known to be pleiotropic, meaning it influences the expression of numerous/many genes throughout many/a range of systems and organs of the body. [3] Vitamin D receptors (VDR) are present in a wide variety of cells in numerous/many systems and most organs in the body (eg: heart, immune system, central and peripheral nervous systems, skeleton, brain, kidneys, skin, prostate and breast). [4] Older individuals/people may have an increased requirement for vitamin D3. [5a] The bodys ability to metabolise vitamin D to its active form may decline with age. [5b] Aging decreases the capacity/ability of the skin to produce vitamin D3 (because the concentration of 7-dehydrocholesterol in the skin decreases with age). [5c] Evidence suggests that by the age of 70yrs, the skins ability to produce vitamin D3 is reduced by approximately 75% compared to younger adults. [6] Vitamin D is required for healthy cell development, differentiation and maturation. [7] Adequate vitamin D is important for the maintenance of a normal healthy immune system. [8] 1,25(OH)2D3 (calcitriol) interacts with immune cells such as monocyte-macrophages, antigen presenting cells, dendritic cells and lymphocytes and induces their differentiation. [9a] Vitamin D enhances/supports/improves the ability of the small intestine to absorb calcium from the diet. [9b] Adequate levels of Vitamin D are necessary for the maintenance of normal healthy calcium metabolism. [9c] Vitamin D is important/necessary/essential for the efficient utilisation of calcium by the body. [9d] Vitamin D is important for the maintenance of strong healthy bones. [10a] Vitamin D plays an important role in the development, growth and mineralization/maintenance of a healthy skeleton. [10b] Vitamin D assists in maintaining healthy plasma calcium and phosphorus concentrations so that skeletal mineralization occurs. [11] Vitamin D is required for the normal healthy growth of growing childrens bones. [12] Vitamin D3 supplementation may help to reduce the risk of falls in older adults/individuals which may help reduce the incidence/risk of fractures. The mechanism is not yet completely understood, however evidence suggests that as well as having a positive influence on calcium absorption, Vitamin D3 may also have a positive influence on postural and/or dynamic balance. [13] Vitamin D3 assists in maintaining healthy skeletal and cardiac muscles possibly due to its role in muscle cell growth and differentiation. [14] Prostate cells have vitamin D receptors and vitamin D3 is involved in healthy prostate cell metabolism/differentiation/maturation. [15] Vitamin D may provide nutritional support for the maintenance of a healthy cardiovascular system and cardiac/heart muscle. [16] In vitro and animal studies suggest that vitamin D3 and the vitamin D receptor VDR are involved in the (inhibitory) regulation of renin transcription, indicating/proposing a possible inverse relationship between vitamin D3 levels and renin production. [17] Adequate levels of vitamin D in pregnancy are/have been associated/linked with healthy/favourable pregnancy outcomes (foetal birth weight, foetal skeletal growth and limb length). [18[ Vitamin D receptor and vitamin D metabolising enzymes are found in the testis, sperm and the male reproductive tract and may have a role in male fertility (including spermatogenesis, sperm maturation and sperm fertilising ability).

How to take it

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

  • The way to take this medicine: Oral

Always read the label. If symptoms persist see your healthcare professional.

Do I need a prescription?

We are unable to tell you if you need a prescription for this medicine. You can ask your pharmacist.This medicine is Not Scheduled.

Reporting side effects

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You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

Disclaimer

The information about this medicine comes from trusted sources.

  • Therapeutic Goods Administration (TGA)
  • Pharmaceutical Benefits Scheme (PBS)
  • GuildLink
  • DrugBank

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