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Brand name: Adefovir Dipivoxil (Apo) TM

Active ingredients: adefovir

What it is used for

ò Adefovir dipivoxil is indicated for the treatment of chronic hepatitis B in patients 12 years of age and older with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease. ò For adult patients, this indication is based on histological, virological, biochemical, and serological responses in adult patients with HBeAg+ and HBeAg-/HBVDNA+ chronic hepatitis B with compensated liver function, and in adult patients with clinical evidence of lamivudine-resistant hepatitis B virus with either compensated or decompensated liver function. ò For adolescent patients (12 to <18 years of age), the indication is based on virological and biochemical responses in patients with HBeAg+ chronic hepatitis B virus with compensated liver function.

How to take it

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

  • The way to take this medicine: Oral
  • Store below 25 degrees Celsius
  • Protect from Moisture
  • Store in Original Container
  • Protect from Heat
  • Shelf lifetime is 24 Months.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

White to off-white, round, flat-faced bevelled edge tablet. Engraved "APO" on one side, "A10" on the other side.

Images are the copyright of the Pharmacy Guild of Australia

Food interactions

For the active ingredient adefovir

  • Take without regard to meals.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Is this medicine subsidised?

This medicine was verified as being available on the PBS (Pharmaceutical Benefits Scheme) on November 1, 2018. To learn more about this subsidy, visit the Pharmaceutical Benefits Scheme (PBS) website.

Pregnant or planning a pregnancy?

For the active ingredient adefovir

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website

Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

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