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Brand name: Endep

Endep is a brand of tablets containing the active ingredient amitriptyline. It is only available with a doctor’s prescription.

Endep is used to treat depression. Endep belongs to a group of medicines called tricyclic antidepressants. It works by increasing the amount of certain chemicals in the brain that are involved in controlling mood. It may take a few weeks of treatment before you feel that your symptoms of depression have improved.

Endep can also be used to treat bed-wetting that is not caused by a physical problem like a bladder problem. Most children show an improvement in the first few days of starting treatment.

Endep tablets are to be swallowed whole with a glass of water. It doesn’t matter whether you take them with food or not.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional. Always read the label. If symptoms persist see your healthcare professional. healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.

Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions.

Active ingredient in this medicine: amitriptyline

Over 65 years of age?

If you are over 65 years of age, there may be specific risks and recommendations for use of this medicine. Please discuss your individual circumstances with your pharmacist, doctor or health professional. For more information read our page on medication safety for older people.

Pack size information

Please select the pack size from the options directly below to view information on the medicine.

Information for medicine and pack size:
Endep 25 mg film-coated tablet, 50

Consumer Medicine Information leaflet:

This leaflet may also be found inside the medicine package. It contains information on side effects, age restrictions and other useful data.

Read leaflet

What this medicine is for

For the treatment of major depression. Nocturnal enuresis where organic pathology has been excluded.

Table of characteristics
Table of characteristics
Active ingredient
Visual appearance 7mm yellow film coated normal convex tablet marked AP/25 on one side, alpha symbol on reverse.

Images are the copyright of the Pharmacy Guild of Australia

Dosage Form Tablet, film coated
Route of administration Oral
Medicine schedule
10 (sample): Prescription Only Medicine, or Prescription Animal Remedy
1000: Prescription Only Medicine, or Prescription Animal Remedy
50: Prescription Only Medicine, or Prescription Animal Remedy
90: Prescription Only Medicine, or Prescription Animal Remedy

There is one type of pack available.

Pack type 1
Pack type 1
Type Blister Pack
Storage temperature Store below 30 degrees Celsius
Storage conditions No information available
Life time 3 Years
This medicine was verified as being available on the PBS (Pharmaceutical Benefits Scheme) on 1 November 2017

The PBS provides a list of government subsidised medicines available to be dispensed to patients. Further information can be found on the Pharmaceutical Benefits Scheme website.

Go to PBS site

Is this medication banned in sport?

Check if you can use your medicine whilst playing sport. Search the Australian Sports Anti-Doping Authority (ASADA) database that provides information about the prohibited status of specific medications and/or the active ingredient based on the current World Anti-Doping Agency (WADA) Prohibited List.

Go to ASADA site

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