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Brand name: Doxsig TM

Active ingredients: doxycycline

What it is used for

Infections caused by the following organisms: Mycoplasma pneumoniae (primary atypical pneumonia); Rickettsiae (Queensland tick typhus, epidemic typhus fever, Q fever, murine endemic typhus fever, Australo-Pacific endemic scrub typhus); Chlamydia psittaci (psittacosis); Chlamydia trachomatis (lymphogranuloma venereum, trachoma, inclusion conjunctivitis). (Doxycycline is indicated in the treatment of trachoma, although the infectious agent is not always eliminated, as judged by immunofluorescence. Inclusion conjunctivitis may be treated with oral doxycycline alone, or in combination with topical agents). Borreliae (relapsing fever). Calymmatobacterium (Donovania) granulomatis (granuloma inguinale). Infections caused by the following Gram-negative microrganisms: Vibrio species (chlorea), Brucella sp. (Brucellosis; in conjunction with streptomycin), Yersinia pestis (plague), Francisella turarenis (tularaemia), Bartonella bacilliformis (Bartonellosis), Bacteroides sp. When penicillin is contraindicated, DOXSIG is an alternative drug in the treatment of infections due to: Treponema pallidum (syphilis); Treponema pertenue (yaws); Neisseria gonorrhoea (see Dosage and Administration). DOXSIG is not the drug of choice in the treatment of any type of staphlococcal infection or infections due to Streptococcus pneumoniae, Haemophilus influenzae, Streptococcus pyogenes, Streptococcus faecalis or any type of enteric bacteria because many strains of these organisms have been shown to be r esistant to doxycycline. DOXSIG should not be used in these infections unless the organism has been shown to be sensitive. For upper respiratory infections due to group A beta-haemolytic streptococci (including prophylaxis of rheumatic fever), penicillin is the usual drug of choice. In acute intestinal amoebiasis, doxycycline may be a useful adjunct to amoebicides. In severe acne, doxycycline may be useful adjunctive therapy. Doxycycline is indicated, in adults and children older than 10 years , as chemoprophylaxis for malaria caused by Plasmodium falciparum and, in combination with other antimalarial agents, against malaria caused by Plasmodium vivax. Doxycycline is only able to suppress malaria caused by P. vivax. As there are relatively few locations where P. vivax does not co-exist to some extent with P. falciparum, it is recommended that doxycycline should be used routinely with other agents, for example, cholorquine

How to take it

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

  • The way to take this medicine: Oral
  • Store below 30 degrees Celsius
  • Protect from Light
  • Shelf lifetime is 3 Years.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

White, film-coated, biconvex tablet scored on one side for oral use, diameter 9.1mm.

Images are the copyright of the Pharmacy Guild of Australia

Food interactions

For the active ingredient doxycycline

  • Avoid alcohol.
  • Avoid milk, calcium containing dairy products, iron, antacids, or aluminum salts 2 hours before or 6 hours after using antacids while on this medication.
  • Take with a full glass of water Do not take calcium, aluminum, magnesium or Iron supplements within 2 hours of taking this medication.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Is this medicine subsidised?

This medicine was verified as being available on the PBS (Pharmaceutical Benefits Scheme) on November 1, 2018. To learn more about this subsidy, visit the Pharmaceutical Benefits Scheme (PBS) website.

Pregnant or planning a pregnancy?

For the active ingredient doxycycline

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website

Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

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