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Brand name: Caelyx TM

Active ingredients: doxorubicin hydrochloride (as pegylated liposomal)

What it is used for

INDICATIONS: For the treatment of: (1) Advanced epithelial ovarian cancer in women who have failed a first-line platinum-based chemotherapy regimen. (2) AIDS-related Kaposi's sarcoma (KS) in patients with low CD4 counts (<200 lymphocytes/cubic mm) and extensive mucocutaneous or visceral disease. As first-line systemic chemotherapy, or as second line chemotherapy in AIDS-KS patients with disease that has progressed with, or in patients intolerant to, prior combination systemic chemotherapy comprising at least two of the following agents: a vinca alkaloid, bleomycin and doxorubicin (or other anthracycline). INDICATIONS AS AT 29 February 2008: CAELYX, as monotherapy, is indicated for the treatment of metastatic breast cancer. CAELYX is also indicated for the treatment of: Advanced epithelial ovarian cancer in women who have failed a first-line platinum-based chemotherapy regimen. AIDS-related Kaposi's sarcoma (KS) in patients with low CD4 counts (<200 lymphocytes/mm3) and extensive mucocutaneous or visceral disease. CAELYX may be used as first-line systemic chemotherapy, or as second line chemotherapy in AIDS-KS patients with disease that has progressed with, or in patients intolerant to, prior combination systemic chemotherapy comprising at least two of the following agents: a vinca alkaloid, bleomycin and doxorubicin (or other anthracycline). Caelyx is also indicated, in combination with bortezomib, for the treatment of progressive multiple myeloma in patients who have received at least one prior therapy and who have already undergone or who are unsuitable for bone marrow transplant.

How to take it

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

  • The way to take this medicine: Intravenous
  • Store at 2 to 8 degrees Celsius
  • Do not Freeze
  • Refrigerate
  • Shelf lifetime is 20 Months.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

Red translucent suspension

Food interactions

For the active ingredient doxorubicin hydrochloride (as pegylated liposomal)

  • Liberal fluid intake to increase urine output and help the excretion of uric acid.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Pregnant or planning a pregnancy?

For the active ingredient doxorubicin hydrochloride (as pegylated liposomal)

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website

Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

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