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Brand name: Methotrexate (DBL)

Methotrexate (DBL) is a medicine containing the active ingredient(s) methotrexate. On this page you will find out more about Methotrexate (DBL), including side effects, age restrictions, food interactions and whether the medicine is subsidised by the government on the pharmaceutical benefits scheme (PBS)

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional. Always read the label. If symptoms persist see your healthcare professional. healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.

Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions.

Active ingredient in this medicine: methotrexate

Pack size information

Please select the pack size from the options directly below to view information on the medicine.

Information for medicine and pack size:
Methotrexate (DBL) 5 mg/2 mL injection solution, 5 x 2 mL vials

Consumer Medicine Information leaflet:

This leaflet may also be found inside the medicine package. It contains information on side effects, age restrictions and other useful data.

Read leaflet

What this medicine is for

Antineoplastic chemotherapy: Methotrexate has a broad spectrum of antineoplastic activity. It is indicated for the treatment of breast cancer, gestational choriocarcinoma, and in patients with chorioadenoma destruens and hydatidiform mole. Methotrexate may be used in combination with other chemotherapeutic agents for the palliative treatment of acute leukaemias, particularly acute lymphoblastic leukaemia. It may also be used in the treatment of Burkitt's lymphoma, advanced stages (III and IV, Peters' Staging System) of lymphosarcoma, especially in children, and in advanced cases of mycosis fungoides. High dose therapy: In high-dose schedules, methotrexate may be effective alone or in combination therapy, in the treatment of epidermoid cancers of the head and neck, osteogenic sarcoma and bronchogenic carcinoma. Calcium folinate (leucovorin calcium) must be used in conjunction with high dose methotrexate therapy. Psoriasis chemotherapy (see WARNING box): Methotrexate may be of value in the symptomatic control of severe, recalcitrant, disabling psoriasis which is not adequately responsive to other forms of treatment. However, due to the high risk associated with its use, methotrexate should be used after the diagnosis has been definitely established, as by biopsy and/or after dermatologic consultation.

Table of characteristics
Table of characteristics
Active ingredient
Visual appearance Yellow solution
Dosage Form Injection, solution
Route of administration Intravenous
Medicine schedule
5x5mg/2mL: Prescription Only Medicine, or Prescription Animal Remedy
5x5mg/2mL(E): Not scheduled. Not considered by committee

There is one type of pack available.

Pack type 1
Pack type 1
Type Vial
Storage temperature Store below 25 degrees Celsius
Storage conditions Protect from Light
Life time 18 Months
This medicine was verified as being available on the PBS (Pharmaceutical Benefits Scheme) on 1 November 2017

The PBS provides a list of government subsidised medicines available to be dispensed to patients. Further information can be found on the Pharmaceutical Benefits Scheme website.

Go to PBS site

Is this medication banned in sport?

Check if you can use your medicine whilst playing sport. Search the Australian Sports Anti-Doping Authority (ASADA) database that provides information about the prohibited status of specific medications and/or the active ingredient based on the current World Anti-Doping Agency (WADA) Prohibited List.

Go to ASADA site

The information displayed on this page is authored by Healthdirect Australia, or obtained from trusted sources.

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Found 11 results

DBL Methotrexate Solution for injection - myDr.com.au

DBL Methotrexate Solution for injection - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

Methotrexate Injection and Tablets (DBL) | myVMC

Methotrexate Injection and Tablets is a cytotoxic, immunosuppressive and anti-inflammatory medicine. It treats cancer, lymphoma and autoimmune disorders.

Read more on myVMC – Virtual Medical Centre website

Leucovorin Calcium Injection USP & Tablets (DBL) | myVMC

Leucovorin Calcium Injection is used for folinic acid rescue therapy, to reduce toxicity of methotrexate treatment. It contains calcium folinate.

Read more on myVMC – Virtual Medical Centre website

DBL Aciclovir Intravenous Infusion (Concentrate for infusion) - myDr.com.au

DBL Aciclovir Intravenous Infusion (Concentrate for infusion) - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

DBL Piperacillin and Tazobactam Injection Powder for infusion - myDr.com.au

DBL Piperacillin and Tazobactam Injection Powder for infusion - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

DBL Cephalothin Sodium for Injection (Powder for injection) - myDr.com.au

DBL Cephalothin Sodium for Injection (Powder for injection) - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

DBL Phenytoin Injection BP Solution for injection - myDr.com.au

DBL Phenytoin Injection BP Solution for injection - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

DBL Fluorouracil Injection BP (Solution for injection) - myDr.com.au

DBL Fluorouracil Injection BP (Solution for injection) - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

DBL Ciprofloxacin Injection For Intravenous Infusion - myDr.com.au

DBL Ciprofloxacin Injection For Intravenous Infusion - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

DBL Sulfamethoxazole 400 mg and Trimethoprim 80 mg Concentrate Injection BP - myDr.com.au

DBL Sulfamethoxazole 400 mg and Trimethoprim 80 mg Concentrate Injection BP - Consumer Medicines Information leaflets of prescription and over-the-counter medicines

Read more on myDr – Consumer Medicine Information website

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