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Brand name: Thiotepa (Sigma) TM

Active ingredients: thiotepa

What it is used for

Thiotepa has been tried with varying results in the palliation of a wide variety of neoplastic diseases. However, the most consistent results have been seen in the following tumours: . adenocarcinoma of the breast or ovary; . for controlling intracavitary effusions secondary to diffuse or localised neoplastic diseases of various serosal cavities and . for the treatment of superficial papillary carcinoma of the urinary bladder. While now largely superseded by other treatments, thiotepa has been effective against other lymphomas, such as lymphosarcoma and Hodgkin's disease. Complete response rates of 27% and 48% were obtained with a dose of30mg thiotepa in the treatment of bladder cancer.

How to take it

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

  • The way to take this medicine: Intravesical
  • Store at 2 to 8 degrees Celsius
  • Refrigerate
  • Protect from Light
  • Do not Freeze
  • Shelf lifetime is 18 Months.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

clear 3 mL Type I glass vials with a West Company 1319/4020/25 bromo butyl 20 mm siliconised grey stopper containing white caked mass or powder. Flip cap is a plane blue/silver 200 mm lid.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Pregnant or planning a pregnancy?

For the active ingredient thiotepa

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website

Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

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