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Brand name: Solu-Medrol Act-O-Vial TM

Listen to the Pronunciation:

Active ingredients: methylprednisolone

What it is used for

When oral therapy is not feasible and the strength, dosage form and route of administration of the drug reasonably lend the preparation to the treatment of the condition, SOLU-MEDROL Powder for Injection is indicated only for intravenous or intramuscular use in the following conditions:,Endocrine Disorders, Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; synthetic analogues may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance)., Acute adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; mineralocorticoid supplementation may be necessary, particularly when synthetic analogues are used)., Preoperatively and in the event of serious trauma or illness, in patients with known adrenal insufficiency or when adrenocortical reserve is doubtful., Shock unresponsive to conventional therapy if adrenocortical insufficiency exists or is suspected., Congenital adrenal hyperplasia, Nonsuppurative thyroiditis, Hypercalcaemia associated with cancer.,Rheumatic Disorders,As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in:, Ankylosing spondylitis, Psoriatic arthritis, Acute and subacute bursitis, Epicondylitis, Synovitis of osteoarthritis, Acute gouty arthritis, Acute nonspecific tenosynovitis, Post-traumatic osteoarthritis, Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low dose maintenance therapy).,Collagen Disease,During an exacerbation or as maintenance therapy in selected cases of:, Systemic lupus erythematosus, Systemic dermatomyositis (polymyositis), Acute rheumatic carditis.,Dermatological Diseases, Bullous dermatitis herpetiformis, Pemphigus, Severe psoriasis, Severe seborrhoeic dermatitis, Exfoliative dermatitis, Mycosis fungoides, Severe erythema multiforme (Stevens-Johnson Syndrome).,Allergic States,Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in:, Bronchial asthma, Drug hypersensitivity reactions, Contact dermatitis, Urticarial transfusion reactions, Atopic dermatitis, Serum sickness, Acute noninfectious laryngeal oedema (adrenaline is the drug of first choice).,Ophthalmic Diseases,Severe acute and chronic allergic and inflammatory processes involving the eye, such as:, Allergic corneal marginal ulcers, Allergic conjunctivitis, Chorioretinitis, Anterior segment inflammation, Herpes zoster ophthalmicus, Iritis, iridocyclitis, Diffuse posterior uveitis and choroiditis, Keratitis, Optic neuritis, Sympathetic ophthalmia.,Gastrointestinal Diseases,To tide the patient over a critical period of the disease in:, Ulcerative colitis (systemic therapy), Regional enteritis (systemic therapy).,Respiratory Diseases, Symptomatic sarcoidosis, Berylliosis, Aspiration pneumonitis, Loefflers syndrome not manageable by other means, Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy.,Haematologic Disorders, Idiopathic thrombocytopenic purpura in adults (IV only; IM administration is contraindicated), Secondary thrombocytopenia in adults, Acquired (autoimmune) haemolytic anaemia, Erythroblastopenia (RBC anaemia), Congenital (erythroid) hypoplastic anaemia.,Neoplastic Diseases,For palliative management of:, Leukaemias and lymphomas in adults, Acute leukaemia of childhood.,Oedematous States, To induce diuresis or remission of proteinuria in the nephrotic syndrome, without uraemia, of the idiopathic type or that due to lupus erythematosus.,Nervous System, Acute exacerbations of multiple sclerosis.,Miscellaneous, Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy., Trichinosis with neurologic or myocardial involvement., SOLU-MEDROL is beneficial as adjunctive therapy in the treatment of acquired immunodeficiency syndrome (AIDS) patients with moderate to severe Pneumocystis jiroveci pneumonia (PCP) when given within the first 72 hours of initial anti-pneumocystis treatment.

How to take it

This medicine is a pack that contains more than one part.

Part 1: Diluent, not applicable

Clear colourless liquid

The way to take this medicine is: Intramuscular. This medicine is given through a needle inserted into the muscle beneath the skin.

Part 2: Injection, powder for

White freeze dried cake in bottom half of vial.

The way to take this medicine is: Intramuscular. This medicine is given through a needle inserted into the muscle beneath the skin.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.

Storage instructions

  • Store below 25 degrees Celsius
  • Protect from Light
  • Shelf lifetime is 2 Years.

Do I need a prescription?

These medicine packs are available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

  • 1 X ACT -O-VIALS with powder 40mg pack

We are unable to tell you if you need a prescription for these medicines. You can ask your pharmacist. This medicine is Not Scheduled.

  • and diluent 1mL in separate chambers pack

Is this medicine subsidised?

This medicine was verified as being available on the PBS (Pharmaceutical Benefits Scheme) on September 1, 2023. To learn more about this subsidy, visit the Pharmaceutical Benefits Scheme (PBS) website.

Pregnant or planning a pregnancy?

For the active ingredient methylprednisolone

This medicine is generally considered safe during pregnancy if taken as directed. During pregnancy, you should discuss your medicine use with your doctor or pharmacist.

Consumer Medicines Information (CMI)

For side effects, taking other medicines and more

Print the CMI.

Listen to the CMI.

Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at

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