Brand name: Aplidin TM
Active ingredients: plitidepsin
What it is used for
Aplidin, in combination with dexamethasone, is indicated for the treatment of patients with relapsed and refractory multiple myeloma who have received at least three prior treatment regimens, including both a proteasome inhibitor and an immunomodulator. Aplidin may be used after two prior lines of therapy if refractory and/or intolerant to both a proteasome inhibitor and an immunomodulator.
How to take it
This medicine is a pack that contains more than one part.
Part 1: Injection, solution
Clear, slightly viscous liquid free of visible particles
The way to take this medicine is: Intravenous Infusion.
Part 2: Injection, intravenous infusion
The powder is a white to off-white power or solid cake
The way to take this medicine is: Intravenous Infusion.
You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.
Always read the label. If symptoms persist see your healthcare professional.
Storage instructions
- Store at 2 to 8 degrees Celsius
- Refrigerate
- Do not Freeze
- Protect from Light
- Shelf lifetime is 60 Months.
Do I need a prescription?
This medicine is available from a pharmacist and requires a prescription. It is
Pregnant or planning a pregnancy?
For the active ingredient plitidepsin
You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.
Download leaflet
For side effects, taking other medicines and more
Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website
Reporting side effects
This medicine is under additional monitoring as it is new or being used in a different way. You can help identify new safety information by reporting any side effects you may get.
- You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems.
- For more information on the Black Triangle Scheme and how to report side effects, see www.tga.gov.au/black-triangle-scheme
