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Brand name: Aplidin TM

Active ingredients: plitidepsin

What it is used for

Aplidin, in combination with dexamethasone, is indicated for the treatment of patients with relapsed and refractory multiple myeloma who have received at least three prior treatment regimens, including both a proteasome inhibitor and an immunomodulator. Aplidin may be used after two prior lines of therapy if refractory and/or intolerant to both a proteasome inhibitor and an immunomodulator.

How to take it

This medicine is a pack that contains more than one part.

Part 1: Injection, solution

Clear, slightly viscous liquid free of visible particles

The way to take this medicine is: Intravenous Infusion.

Part 2: Injection, intravenous infusion

The powder is a white to off-white power or solid cake

The way to take this medicine is: Intravenous Infusion.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.

Storage instructions

  • Store at 2 to 8 degrees Celsius
  • Refrigerate
  • Do not Freeze
  • Protect from Light
  • Shelf lifetime is 48 Months.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website

Reporting side effects

This medicine is under additional monitoring as it is new or being used in a different way. You can help identify new safety information by reporting any side effects you may get.

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