What it is used for

Adults (=18 years),Prevention of Cardiovascular Disease APO-EZETIMIBE/SIMVASTATIN is indicated in patients with coronary heart disease (CHD) and a history of acute coronary syndrome (ACS) taking their maximum tolerated dose of simvastatin and in need of additional lowering of LDL-C in the expectation of a modest further reduction in the risk of cardiovascular events following at least one year of therapy (see Clinical Trials).,Primary Hypercholesterolaemia APO-EZETIMIBE/SIMVASTATIN is indicated as adjunctive therapy to diet in patients with primary (heterozygous familial and non-familial) hypercholesterolaemia or mixed hyperlipidaemia where use of a combination product is appropriate: Patients not appropriately controlled with a statin or ezetimibe alone. Patients already treated with a statin and ezetimibe.,Homozygous Familial Hypercholesterolaemia (HoFH) APO-EZETIMIBE/SIMVASTATIN is indicated in patients with HoFH. Patients may also receive adjunctive treatments (e.g., LDL apheresis). Children and Adolescents 10-17 years (pubertal status: boys Tanner Stage II and above and girls who are at least one year post- menarche),Heterozygous Familial Hypercholesterolaemia (HeFH) APO-EZETIMIBE/SIMVASTATIN is indicated as adjunctive therapy to diet in adolescent patients (10-17 years old) with heterozygous familial hypercholesterolaemia where use of a combination product is appropriate: Patients not appropriately controlled with a statin or ezetimibe alone. Patients already treated with a statin and ezetimibe.,Homozygous Familial Hypercholesterolaemia (HoFH) APO-EZETIMIBE/SIMVASTATIN is indicated in adolescent patients (10-17 years old) with HoFH. Patients may also receive adjunctive treatments (e.g., LDL apheresis).

How to take it

The way to take this medicine is: Oral. This medicine is taken by mouth.

• Store below 25 degrees Celsius
• Store in Original Container
• Shelf lifetime is 24 Months.
• Store below 25 degrees Celsius
• Store in Original Container
• Shelf lifetime is 18 Months.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

Light tan, mottled, round about 10 mm, biconvex tablets. Marking 513 on one side.

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Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine. open tool tip to find out more

Pregnant or planning a pregnancy?

For the active ingredient ezetimibe + simvastatin

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.