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Brand name: Lynparza TM

Active ingredients: olaparib

What it is used for

Ovarian cancer,LYNPARZA is indicated as monotherapy for the:, maintenance treatment of adult patients who have advanced, high-grade, epithelial ovarian, fallopian tube or primary peritoneal cancer with a deleterious or suspected deleterious, breast cancer susceptibility gene (BRCA) mutation (germline or somatic), which is in response (complete or partial) to first-line platinum-based chemotherapy., maintenance treatment of adult patients who have platinum-sensitive relapsed, high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer which is in response (complete or partial) after platinum-based chemotherapy. Prior treatment must have included at least 2 courses of platinum-based regimens.,LYNPARZA in combination with bevacizumab is indicated for the:, maintenance treatment of adult patients who have advanced, epithelial ovarian, fallopian tube or primary peritoneal cancer which is in response (complete or partial) to first-line platinumbased chemotherapy and whose cancer is associated with homologous recombination deficiency (HRD)-positive status defined by either:,- a deleterious or suspected deleterious BRCA mutation (germline or somatic), and/or,- genomic instability,Breast cancer,LYNPARZA is indicated as monotherapy for the:, treatment of adult patients with germline BRCA-mutated HER2-negative metastatic breast cancer who have previously been treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting. Germline BRCA mutation (gBRCAm) status should be determined by an experienced laboratory using a validated test method.,LYNPARZA is indicated as monotherapy for the:, adjuvant treatment of adult patients with BRCA-mutated HER2-negative high risk early breast cancer who have previously been treated with neoadjuvant or adjuvant chemotherapy (see sections 4.2 -Dose and method of administration and 5.1 -Pharmacodynamic properties).,Prostate cancer,LYNPARZA is indicated as monotherapy for the:, treatment of adult patients who have metastatic castration-resistant prostate cancer (mCRPC) with a deleterious or suspected deleterious BRCA mutation (germline or somatic), which has progressed following prior therapy that included a new hormonal agent.,LYNPARZA in combination with abiraterone and either prednisone or prednisolone is indicated for the:, treatment of adult patients who have mCRPC with a deleterious or suspected deleterious BRCA mutation (germline or somatic).,Adenocarcinoma of the pancreas,LYNPARZA is indicated as monotherapy for the:, maintenance treatment of adult patients who have metastatic pancreatic adenocarcinoma with a deleterious or suspected deleterious gBRCAm, which has not progressed on at least 16 weeks of a first-line platinum-based chemotherapy regimen.

How to take it

The way to take this medicine is: Oral. This medicine is taken by mouth.

  • Store below 30 degrees Celsius
  • Protect from Moisture
  • Store in Original Container
  • Shelf lifetime is 4 Years.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

Green to green/grey film-coated, oval, biconvex tablet, debossed with 'OP 150' on one side and plain on the reverse

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Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Is this medicine subsidised?

This medicine was verified as being available on the PBS (Pharmaceutical Benefits Scheme) on April 1, 2024. To learn more about this subsidy, visit the Pharmaceutical Benefits Scheme (PBS) website.

Pregnant or planning a pregnancy?

For the active ingredient olaparib

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Consumer Medicines Information (CMI)

For side effects, taking other medicines and more

Print the CMI.

Listen to the CMI.


Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

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