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Active ingredients: exemestane
What it is used for
Sequential adjuvant treatment of oestrogen receptor positive early breast cancer in postmenopausal women who have received prior adjuvant tamoxifen therapy.,Treatment of oestrogen receptor positive advanced breast cancer in women with natural or induced postmenopausal status whose disease has progressed following antioestrogen therapy.
How to take it
You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.
- The way to take this medicine: Oral
- Store below 30 degrees Celsius
- Shelf lifetime is 3 Years.
Always read the label. If symptoms persist see your healthcare professional.
White to off-white, circular, biconvex, sugar-coated tablets
Images are the copyright of the Pharmacy Guild of Australia
For the active ingredient exemestane
- High-fat meals increase plasma exemestane concentrations by approximately 40%.
Do I need a prescription?
This medicine is available from a pharmacist and requires a prescription. It is
Is this medicine subsidised?
This medicine was verified as being available on the PBS (Pharmaceutical Benefits Scheme) on February 1, 2019. To learn more about this subsidy, visit the Pharmaceutical Benefits Scheme (PBS) website.
Pregnant or planning a pregnancy?
For the active ingredient exemestane
You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.
For side effects, taking other medicines and more
Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website
Reporting side effects
You can help ensure medicines are safe by reporting the side effects you experience.
You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems
Breast cancer and oestrogen - Better Health Channel
There are different types of breast cancer, and around 70 per cent are sensitive to the female sex hormone oestrogen.
Read more on Better Health Channel website
Hormonal Treatment - Counterpart
Find information on the various hormonal treatments that can be used in the treatment of some types of breast cancer.
Read more on Counterpart - Women supporting women with cancer website
Breast cancer - myDr.com.au
Breast cancer is the most common cancer diagnosed in Australian women.The good news is that with advances in treatment and diagnosis, more women are surviving breast cancer than ever before.
Read more on myDr website
Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women | Cochrane
Advanced (or metastatic) breast cancer is cancer that has spread beyond the breast and regional lymph node areas. Breast cancer can progress to metastatic disease despite the person undergoing a range of therapies given after initial treatment, such as surgery, chemotherapy or radiation therapy. Metastatic breast cancer is treatable but it is not curable. Most breast cancer is sensitive to the female hormone oestrogen. Sensitive cancer cells need oestrogen to stay alive and removal of oestrogen from the body, or stopping any circulating oestrogen getting to the cancer cells, is very effective treatment for hormone-sensitive breast cancers. Endocrine (hormonal) therapy removes the influence of oestrogen on breast cancer cells. Hormonal treatments for advanced breast cancer include tamoxifen, the progestins megestrol acetate and medroxyprogesterone acetate, and aromatase inhibitors (AIs). AIs reduce the body's ability to make (synthesise) oestrogen and have tumour-regressing effects. The AIs in current clinical use include anastrozole, exemestane, and letrozole.
Read more on Cochrane (Australasian Centre) website
Vaginal health after breast cancer: A guide for patients - Australasian Menopause Society
Women who have had breast cancer treatment before menopause might find they develop symptoms such as hot flushes, night sweats, joint aches and vaginal dryness.These are symptoms of low oestrogen, which occur naturally with age, but may also occur in younger women undergoing treatment for breast cancer. These changes are called the genito-urinary syndrome of menopause (GSM), which was previously known as atrophic vaginitis.Unlike some menopausal symptoms, such as hot flushes, which may go awa
Read more on Australasian Menopause Society website