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Brand name: Mabthera TM

Active ingredients: rituximab

What it is used for

Non-Hodgkin's Lymphoma: MABTHERA is indicated for treatment of patients with: CD20 positive, previously untreated, Stage III/IV follicular, B-cell non-Hodgkin's lymphoma. CD20 positive, relapsed or refractory low grade or follicular, B-cell non-Hodgkin's lymphoma, CD20 positive, diffuse large B-cell non-Hodgkin's lymphoma, in combination with chemotherapy. Chronic Lymphocytic Leukaemia: MABTHERA is indicated for the treatment of patients with CD20 positive chronic lymphocytic leukaemia (CLL) in combination with chemotherapy. Rheumatoid Arthritis: MABTHERA (rituximab) in combination with methotrexate is indicated for the treatment of adult patients with severe, active rheumatoid arthritis who have had an inadequate response or intolerance to at least one tumour necrosis factor (TNF) inhibitor therapy. MABTHERA has been shown to reduce the rate of progression of joint damage as measured by x-ray when given in combination with methotrexate. Granulomatosis with polyangiitis (Wegener's ) (GPA) and Microscopic polyangiitis (MPA). MABTHERA in combination with glucocorticoids is indicated for the induction of remission in patients with severely active Granulomatosis with polyangiitis (GPA, also known as Wegener's granulomatosis) and Microscopic polyangiitis (MPA). The efficacy and safety of retreatment with MABTHERA have not been established.

How to take it

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

  • The way to take this medicine: Intravenous
  • Store at 2 to 8 degrees Celsius
  • Refrigerate
  • Protect from Light
  • Do not Freeze
  • Lifetime is 30 Months.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

Clear to opalescent, colourless to pale yellow liquid.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Pregnant or planning a pregnancy?

For the active ingredient rituximab

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf)

Disclaimer

The information about this medicine comes from trusted sources.

  • Therapeutic Good's Administration (TGA)
  • Pharmaceutical Benefits Scheme (PBS)
  • GuildLink
  • DrugBank

healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.

Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions.

See also

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