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Brand name: Primaxin TM

Active ingredients: imipenem + cilastatin

What it is used for

PRIMAXIN is indicated for the treatment of serious infections caused by susceptible strains of micro-organisms in the diseases listed below: 1. Lower respiratory tract infections. 2 Intra-abdominal infections. 3. Gynaecological infections. 4. Bacterial septicaemia. 5. Bone and joint infections. 6. Skin and skin structure infections. 7. Endocarditis. 8. Polymicrobial infections. PRIMAXIN is indicated for polymicrobial infections including those in which S. pneumoniae (pneumonia, septicaemia), Group A beta-haemolytic streptococcus (skin and skin structure), or non-penicillinase-producing S. aureus is one of the causative organisms. However monobacterial infections due to these organisms are usually treated with narrower spectrum antibiotics, such as penicillin G. Efficacy against polymicrobial infection in the immunocompromised host has not yet been established. Although clinical improvement has been observed in patients with cystic fibrosis, chronic pulmonary disease, and lower respiratory tract infections caused by Pseudomonas aeruginosa, bacterial eradication may not necessarily be achieved. As with other beta-lactam antibiotics, strains of Pseudomonas aeruginosa may develop resistance rapidly on treatment with PRIMAXIN. When clinically appropriate during therapy of Pseudomonas aeruginosa infections, periodic susceptibility testing should be done. Infections resistant to other antibiotics, for example, cephalosporins, penicillin, and aminoglycosides, may respond to treatment with PRIMAXIN. PRIMAXIN is not indicated for the treatment of meningitis.

How to take it

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

  • The way to take this medicine: Intravenous
  • Store below 25 degrees Celsius
  • Lifetime is 0 .

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

White powder

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4: Prescription Only Medicine.

Is this medicine subsidised?

This medicine may be subsidised which may make it cheaper. To learn more about this subsidy, visit the Pharmaceutical Benefits Scheme (PBS) website.

Pregnant or planning a pregnancy?

For the active ingredient imipenem + cilastatin

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf)


The information about this medicine comes from trusted sources.

  • Therapeutic Good's Administration (TGA)
  • Pharmaceutical Benefits Scheme (PBS)
  • GuildLink
  • DrugBank

healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.

Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions.

See also

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