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Brand name: Intron A TM

Active ingredients: interferon alfa-2b

What it is used for

Hairy cell leukaemia: for the treatment of hairy cell leukaemia in splenectomised or non-splenectomised patients. Kaposi's sarcoma in AIDS: for the treatment of Kaposi's sarcoma in patients with acquired immune deficiency syndrome (AIDS). Chronic myelogenous leukaemia: for the treatment of Philadelphia chromosome positive chronic myelogenous leukaemia in the chronic phase. Multiple myeloma: for the maintenance of control of multiple myeloma once control has been achieved by chemotherapy. The effect on overall survival has not as yet been determined. Follicular non-Hodgkin's lymphoma: as an adjuvant treatment of high tumour burden Stage III or IV follicular non-Hodgkin's lymphoma in conjunction with an appropriate chemotherapy regimen. In controlled clinical trials in which efficacy was demonstrated, anthracycline chemotherapy was employed. Malignant melanoma: as an adjuvant therapy of malignant melanoma following surgery in patients who are at high risk of recurrence. The potential benefit to the patient should be assessed carefully. Although toxicity of the treatment may be substantial, for most patients, the benefit of therapy outweighed the risk. Chronic hepatitis B: for the treatment of adults with histologically proven compensated chronic active hepatitis B. Patients should be serum HBsAg positive and have evidence of HBV replication (such as serum HBeAg positive) and raised serum alanine aminotransferase (ALT) levels (>3 times the upper limit of the reference range) for at least 6 months. [See Pharmacology for response rate]. Chronic hepatitis C: for the treatment of histologically proven compensated chronic hepatitis due to hepatitis C (HCV antibody positive) in adult patients with persistently elevated serum alanine aminotransferase (ALT). Studies in these patients demonstrate that Intron A Injection therapy can produce normalisation of serum ALT, clearance of serum HCV RNA and improvement in liver histology.

How to take it

The way to take this medicine is: Subcutaneous. This medicine is injected, usually with a short needle or pen-like device, into the fat just beneath the skin.

  • Store at 2 to 8 degrees Celsius
  • Refrigerate
  • Do not Freeze
  • Shelf lifetime is 18 Months.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.

Visual appearance

Clear to opalescent, colourless to light yellow solution, essentially free of visible particles.

Food interactions

For the active ingredient interferon alfa-2b

  • Avoid alcohol.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Pregnant or planning a pregnancy?

For the active ingredient interferon alfa-2b

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Download leaflet

For side effects, taking other medicines and more

Download consumer medicine information leaflet (pdf) from the Therapeutic Goods Administration (TGA) website

Reporting side effects

You can help ensure medicines are safe by reporting the side effects you experience.

You can report side effects to your doctor, or directly at

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