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Brand name: Evusheld TM

Active ingredients: tixagevimab, cilgavimab

What it is used for

Pre-exposure prophylaxis,EVUSHELD (tixagevimab and cilgavimab) has provisional approval for the pre-exposure prophylaxis of COVID-19 in adults and adolescents aged 12 years and older weighing at least 40 kg,,- Who have moderate to severe immune compromise due to a medical condition or receipt of immunosuppressive medications or treatments that make it likely that they will not mount an adequate immune response to COVID-19 vaccination or,- For whom vaccination with any approved COVID-19 vaccine is not recommended due to a history of severe adverse reaction (e.g., severe allergic reaction) to a COVID-19 vaccine(s) and/or COVID-19 vaccine component(s).,See Section 4.2 Dose and method of administration and Section 5.2 Pharmacokinetic properties.,EVUSHELD is not recommended as a substitute for vaccination in individuals for whom COVID-19 vaccination is recommended.,This decision has been made on the basis of short-term efficacy and safety data. Continued approval depends on the evidence of longer-term efficacy and safety data from ongoing clinical trials.,Treatment,EVUSHELD has provisional approval for the treatment of adults with COVID-19, who do not require supplemental oxygen and who are at increased risk of progressing to severe COVID-19. See Section 4.2 Dose and method of administration and Section 5.2 Pharmacokinetic properties.,This decision has been made on the basis of short-term efficacy and safety data. Continued approval depends on the evidence of longer-term efficacy and safety data from ongoing clinical trial.

How to take it

This medicine is a pack that contains more than one part.

Part 1: Injection, solution

Clear to opalescent, colourless to slightly yellow solution

The way to take this medicine is: Intramuscular. This medicine is given through a needle inserted into the muscle beneath the skin.

Part 2: Injection, solution

Clear to opalescent, colourless to slightly yellow solution

The way to take this medicine is: Intramuscular. This medicine is given through a needle inserted into the muscle beneath the skin.

You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.

Always read the label. If symptoms persist see your healthcare professional.

Storage instructions

  • Store at 2 to 8 degrees Celsius
  • Protect from Light
  • Do not Freeze
  • Do not Shake
  • Shelf lifetime is 24 Months.

Do I need a prescription?

This medicine is available from a pharmacist and requires a prescription. It is Schedule 4 : Prescription Only Medicine.

Pregnant or planning a pregnancy?

For the active ingredient tixagevimab

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

For the active ingredient cilgavimab

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Consumer Medicines Information (CMI)

For side effects, taking other medicines and more

Print the CMI.

Listen to the CMI.


Reporting side effects

This medicine is under additional monitoring as it is new or being used in a different way. You can help identify new safety information by reporting any side effects you may get.

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