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Hand, foot and mouth disease symptoms

The most common symptoms of hand, foot and mouth disease are:

  • fever
  • tiny blisters in the mouth and on the hands and feet, and sometimes in the nappy area in infants
  • sore throat
  • runny nose
  • cough
  • loss of appetite
  • tiredness.

The symptoms of hand, foot and mouth disease usually start to appear 3 to 7 days after a person is infected, and typically last for 7 to 10 days.

Symptoms are usually mild

Blisters inside the mouth are often the most troublesome symptoms, because they can make eating and drinking quite painful. However, in some cases, especially in adults, symptoms are so mild that they are not noticeable.

In very rare cases, coxsackievirus (which causes hand, foot and mouth disease) can cause serious illnesses that affect the heart, brain, lungs or eyes.

What are the signs of a serious infection?

Young children are at higher risk of serious infection than older children, teenagers and adults. Signs that a person might have a more serious form of hand, foot and mouth disease include any of the following:

  • persistent fever (38°C or above for 72 hours or more)
  • abnormal movements / jerking movements
  • rapid breathing
  • excessive tiredness, drowsiness
  • excessive irritability
  • difficulty walking.

If any of these signs are present, see your doctor urgently.

Differences between hand, foot and mouth and foot-and-mouth disease

Hand, foot and mouth disease is a completely different disease to foot-and-mouth disease, which only affects animals. The name is the only similarity.

Last reviewed: November 2016

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Hand, foot and mouth disease

Hand, foot and mouth disease (HFMD) is a mild viral infection caused by different human viruses, for example, Coxsackie A, enterovirus and echovirus.

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Hand, Foot and Mouth disease

Hand, foot and mouth disease is a common viral infection which is easily passed from person to person. It usually causes a mild illness but rarely causes serious illness. It is notrelated to the foot and mouth disease that affects animals. Good hygiene helps prevent infection.

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Hand, foot and mouth disease | Raising Children Network

Hand, foot and mouth disease is a common childhood illness. It comes up as mouth ulcers and blisters on your childs hands and feet. Its usually harmless.

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Find out what is hand, foot and mouth disease and links to trusted information on it's symptoms, diagnosis and treatment.

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Hand, foot and mouth disease (HFMD) is a common childhood illness causing mouth sores and a skin rash. Read about the symptoms, treatment and how to prevent infection by this viral illness.

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Hand, foot and mouth disease has nothing to do with cattle, it is a common virus typically suffered by young children

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Parenting and Child Health - Health Topics - Hand, foot and mouth disease

Hand, foot and mouth disease is very common, and usually is a mild illness. It is not related to the disease of a similar name that affects cattle, sheep, goats, pigs and other 'cloven-hooved' animals.

Read more on Women's and Children's Health Network website


Parechovirus is a virus closely related to enteroviruses. Enteroviruses cause illnesses such as diarrhoea, common colds, and hand, foot and mouth disease (not as common). Good hygiene is essential to help prevent spread of the infection.

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