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Monkeypox

12-minute read

If you have recently returned from overseas or been in contact with someone diagnosed with mpox (monkeypox) and you develop symptoms, seek urgent medical attention. Contact your doctor or local hospital.

Key facts

  • Mpox is a rare disease caused by the mpox virus, which is related to the smallpox virus.
  • Mpox does not easily spread unless there is extended close contact.
  • Mpox usually causes a mild illness and resolves within 2 to 4 weeks, but sometimes causes serious illness, which is more likely in young children, during pregnancy and in people with low immunity.
  • The rash goes through several stages, ending with pustules which crust and fall off.
  • Treatment is aimed at relieving symptoms and includes simple pain medicines and staying hydrated.

What is mpox?

Mpox (previously called monkeypox) is a rare infectious disease caused by the mpox virus. This virus is related to the virus that causes smallpox.

Mpox is mostly found in tropical rainforest areas of Central and West Africa. outside of Africa are usually linked to travellers who visit that region and spread the infection when they leave. Since May 2022, there has been increased spread of mpox in many countries in Europe and North America. Mpox has also been reported within Australia.

How does mpox spread?

You can catch mpox after having close contact with an infected person, infected animal, or materials contaminated with the virus.

Person-to-person spread

You can catch mpox from an infected person by:

Animal-to-person spread

Mpox is known as a zoonotic disease, which means that this virus spreads between animals and humans.

Outside Africa, animal-to-human transmission is generally rare. In Africa, mpox may be found in some wild animals, such as rats or squirrels.

Mpox can spread from animals to people, through:

Mpox can also spread during pregnancy through the placenta to an unborn baby.

What are the symptoms of mpox?

First symptoms of mpox include feeling generally unwell with ‘flu-like’ symptoms. The symptoms of mpox are usually mild and most people recover within 2 to 4 weeks.

Early (non-rash) symptoms

Early symptoms of mpox include:

Symptoms begin 5 to 21 days after exposure to the virus.

Onset of rash

Usually, the rash develops 1 to 5 days after a fever and other non-rash symptoms.

The mpox virus causes a specific type of rash, that sometimes looks similar to large chickenpox blisters.

The mpox rash usually appears similar to the images bellow.

Progression of rash

As the disease progresses, your rash goes through stages and changes appearance. Your rash starts off as flat red spots. It then develops into pustules (sores filled with yellowish fluid) and then it becomes crusty, scabs and falls off.

The rash may occur on any part of your body, including your face and inside your mouth, your chest, back, arms and hands, legs and feet and the genital and perianal regions (around your anus). The rash can be painful, especially if the sores or blisters join up, or if you have sores in your mouth or in or around your rectum (bottom end of your colon).

Some people have just a few sores, while others can have several thousand. The sizes of your sores can also vary from small to very large.

In rare cases you may not develop a rash. Instead, you may have rectal pain, infection or bleeding.

Mpox can potentially cause a serious illness. The risk of more severe symptoms is higher for infants, young children, people who are pregnant or with reduced immunity.

CHECK YOUR SYMPTOMS — Use the Symptom Checker and find out if you need to seek medical help.

How soon after exposure to mpox will I develop symptoms?

Usually you will develop symptoms 7 to 14 days after you have been exposed to a person with mpox.

It can take as little as 5 days or as long as 21 days after exposure to develop any symptoms. The time it takes for symptoms to appear is called the incubation period.

When should I see my doctor?

Contact your doctor or local hospital for urgent medical attention if you develop the symptoms of mpox or similar ones and:

Phone ahead, wear a face mask, cover any sores and avoid close contact with other people when you visit the doctor or hospital.

Isolate at home and avoid close physical and intimate contact with others until you get medical advice.

Mpox is a nationally notifiable disease. This means that your doctor must tell the

Department of Health and Aged Care if you have a diagnosis of mpox. The Department needs to monitor and track all cases of mpox in order to find outbreaks and improve healthcare responses.

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How is mpox diagnosed?

Your healthcare professional can diagnose you with mpox by collecting some fluid from the blisters or the scabs of your rash. Your sample will be sent to a laboratory and tested for mpox. You should isolate at home until your doctor notifies you of your results.

How is mpox treated?

Most people have mild mpox and do not need specific treatment, although your doctor may prescribe treatment for symptoms or complications. For example, you may need pain medicines or antibiotics if you develop a skin infection from your rash.

If you have severe mpox or serious complications, you may need antiviral medicines, intravenous (IV) fluids or other medicines. Depending on your situation you may need treatment at a hospital that can give you the appropriate care or at an outpatient clinic.

You should isolate at home until all your blisters or sores have healed and a healthy layer of skin has grown over the sore.

Can mpox be prevented?

How you can protect yourself from getting mpox:

If you are infected with mpox you can help to prevent spreading it:

Contact tracing and isolation of infected people can help prevent the spread of monkeypox.

Can I be vaccinated for mpox?

There are 2 smallpox vaccines approved for use in Australia that can help protect you from mpox disease:

  1. 3rd generation JYNNEOS®
  2. 2nd generation ACAM2000™ — only suitable for healthy, non-pregnant adults

These vaccines can be given:

It’s best to have the vaccine before you are exposed to the virus. Your doctor will recommend 2 doses, around 28 days apart, and ideally 2 weeks before you come into contact with the virus.

If you don’t have the vaccine before you come into contact with the mpox virus, you have the best chance of avoiding the disease if you are vaccinated within 4 days after exposure.

You can still catch mpox even if you have been vaccinated.

JYNNEOS is the preferred vaccine because it is easier to take and has fewer adverse (side) effects.

The Australian Technical Advisory Group on Immunisation (ATAGI) has identified groups of people at higher risk of catching mpox disease. They recommend that people who belong to these at-risk groups see their doctor for vaccination:

More information on the mpox vaccine and how to access vaccination is available from the Department of Health and Aged Care.

Complications of mpox

Complications of mpox include severe dehydration from vomiting or diarrhoea. You may also be unable to drink enough because of sores in your mouth.

Other serious complications of mpox include secondary infections such as:

Most people will recover from mpox without problems.

Larger skin sores may leave a scar when they heal.

Rarely, death may occur.

Resources and support

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