Artiss™
Active ingredients: Aprotinin + factor XIII + fibrinogen, human thrombin + calcium chloride
Consumer medicine information
Read the CMI leaflet (Opens in new tab) for facts you need to know before, during and after taking your medicine.
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What this medicine is used for
ARTISS is indicated to adhere autologous skin grafts in burn patients. ARTISS is indicated to adhere tissue flaps during rhytidectomy (face-lift). Artiss is not indicated for haemostasis
Source: ARTG
Storage conditions
- Shelf lifetime is 2 Years
- Store below minus 18 degrees Celsius (deep freeze)
- Store in a deep freeze
Source: ARTG
How to use this medicine
Non-composite pack
This medicine contains one component only.
Component
- Solution
- Topical
- ARTISS is presented in a prefilled double-chamber syringe package with one set of sterile accessory devices (DUO SET), under deep-frozen state. The syringe is designed for simultaneous application of the Sealer Protein Solution & Thrombin Solution.
Source: ARTG
Do I need a prescription?
Not scheduled medicines: We are unable to tell you if you need a prescription for these medicines. You can ask your pharmacist. These medicines are Not Scheduled.
- 10 mL (5 mL sealer protein solution + 5 mL thrombin solution)
- 2 mL (1 mL sealer protein solution + 1 mL thrombin solution)
- 4 mL (2 mL sealer protein solution + 2 mL thrombin solution)
Source: ARTG
Is this medicine subsidised?
This medicine is not listed on the Pharmaceutical Benefits Scheme (PBS). Talk to your pharmacist about how much it will cost.
Source: PBS
Over 65?
For the active ingredients: Aprotinin + factor XIII + fibrinogen, human thrombin + calcium chloride
If you are over 65 years of age, there may be specific risks and recommendations for use of this medicine. Please discuss your individual circumstances with your pharmacist, doctor or health professional. For more information read our page on medication safety for older people.
Source: AHT
Pregnant or planning a pregnancy?
For the active ingredients: Aprotinin + factor XIII + fibrinogen, human thrombin + calcium chloride
You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.
Source: AHT
Reporting side effects
If you experience a side effect from this medicine, tell your doctor or pharmacist. Or report it directly to the TGA (Therapeutic Goods Administration).
You can report side effects to your doctor, or directly at Report an adverse event or safety problem (Opens in new tab)
Source: ARTG
Data sources
- Australian Health Thesaurus (AHT) (Opens in new tab) – Last updated on 3 August 2026
- Australian Medicines Terminology (AMT) (Opens in new tab) – Last updated on 3 August 2026
- Australian Register of Therapeutic Goods (ARTG) (Opens in new tab) – Last updated on 3 August 2026
- Pharmaceutical Benefits Scheme (PBS) (Opens in new tab) – Last updated on 3 August 2026
- Medicines Information Pty Ltd (Opens in new tab) – Last updated on 4 March 2026
Disclaimer
Healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.
Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions (Opens in new tab).
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