Twinrix™
Active ingredients: Hepatitis A + hepatitis B vaccine
Consumer medicine information
Read the CMI leaflet (Opens in new tab) for facts you need to know before, during and after taking your medicine.
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What this medicine is used for
TWINRIX (720/20) is indicated for active immunisation against hepatitis A and hepatitis B virus infection in adults and children from 1 year of age. TWINRIX Junior (360/10) is indicated for use in children aged 1 to 15 years.,Immunisation against hepatitis A is recommended in the following individuals : Travellers: Persons travelling to areas of intermediate or high endemicity for hepatitis A. This includes all developing countries.,Armed Forces: Armed forces personnel who travel to higher endemicity areas or to areas where hygiene is poor, have an increased risk of HAV infection.,Persons for whom hepatitis A is an occupational hazard or for whom there is an increased risk of transmission. These include:,employees in day-care centres particularly in situations where children have not been toilet trained,teachers and other close contacts of the intellectually disabled,staff and residents of residential facilities for the intellectually disabled,healthcare workers and teachers in remote Aboriginal and Torres Strait Islander communities,nursing staff and other healthcare workers in contact with patients in paediatric wards, infectious diseases wards, emergency rooms and intensive care units,sewerage workers,food handlers, since food hygiene procedures and food processing methods are not always adequate to protect from contamination from food handlers,Homosexual men: Increased incidence of hepatitis A infection among homosexual males suggests that the disease may be sexually transmitted in this group.,Contacts of infected persons: Since virus shedding from infected persons may occur for a prolonged period, active immunisation of close contacts is recommended. The use of vaccine in outbreak control has been shown to be more effective than the use of immunoglobulin.,Specific population groups known to have a higher incidence of hepatitis A: eg. Australian Aboriginals, those in settings with recognised community-wide HAV epidemics.,Individuals with chronic liver disease and recipients of liver transplants, as hepatitis A infection is likely to be more severe in these groups. Many injecting drug users will have pre-existing liver disease from hepatitis B or hepatitis C infection.,Recipients of blood products, such as Factor VIII concentrates.,Immunisation against hepatitis B is recommended in the following individuals:,Persons for whom hepatitis B is an occupational hazard or for whom there is an increased risk of transmission. These include:,healthcare workers directly involved in patient care, or in the handling of human blood or tissue,embalmers,staff and residents of residential facilities for the intellectually disabled,inmates of long term correctional facilities and staff of correctional facilities,Individuals with chronic liver disease and/or hepatitis C.,Haemodialysis patients and recipients of certain blood products such as Factor VIII concentrates.,Sexually active homosexual men and persons with multiple sexual partners: e.g. clients of STD (sexually transmitted disease) clinics. Sexual risk occurs in susceptible (anti-HBs negative) partners of HBV carriers and patients with acute hepatitis B.,Abusers of injectable drugs.,Close residential contacts of deinstitutionalised intellectually disabled individuals who are HBV carriers.,Household contacts of patients with acute hepatitis B and chronic hepatitis B carriers.,Others in whom vaccination against hepatitis B might be justified,Police and members of the armed forces,Travellers to areas of high endemicity for hepatitis B,Participants in contact sportsTwinrix (720/20) is indicated for active immunisation against hepatitis A and hepatitis B virus infection in adults and children from 1 year of age. Twinrix Junior (360/10) is indicated for use in children aged 1 to 15 years.
Source: ARTG
Storage conditions
- Shelf lifetime is 3 Years
- Store at 2 to 8 degrees Celsius
- Do not Freeze
Source: ARTG
How to use this medicine
Non-composite pack
This medicine contains one component only.
Component
- Injection, suspension
- Intramuscular
- fine white deposit in a clear colouless supernatant. The precipitate is easily resuspended when shaken. Once shaken, the vaccine is slightly opaque.
Source: ARTG
Do I need a prescription?
These medicine packs are available from a pharmacist and requires a prescription. It is Schedule 4: Prescription Only Medicine.
- 1mL x 1
- 1mL x 10
Source: ARTG
Is this medicine subsidised?
This medicine is not listed on the Pharmaceutical Benefits Scheme (PBS). Talk to your pharmacist about how much it will cost.
Source: PBS
Pregnant or planning a pregnancy?
For the active ingredient: Hepatitis A + hepatitis B vaccine
You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.
Source: AHT
Reporting side effects
If you experience a side effect from this medicine, tell your doctor or pharmacist. Or report it directly to the TGA (Therapeutic Goods Administration).
You can report side effects to your doctor, or directly at Report an adverse event or safety problem (Opens in new tab)
Source: ARTG
Data sources
- Australian Health Thesaurus (AHT) (Opens in new tab) – Last updated on 3 August 2026
- Australian Medicines Terminology (AMT) (Opens in new tab) – Last updated on 3 August 2026
- Australian Register of Therapeutic Goods (ARTG) (Opens in new tab) – Last updated on 3 August 2026
- Pharmaceutical Benefits Scheme (PBS) (Opens in new tab) – Last updated on 3 August 2026
- Medicines Information Pty Ltd (Opens in new tab) – Last updated on 4 March 2026
Disclaimer
Healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.
Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions (Opens in new tab).
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