Depo-Nisolone™

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INDICATIONS AS AT 17 NOVEMBER 2004: A.For Intramuscular Administration. When oral therapy is not feasible and the strength, dosage form and route of administration of the drug reasonably lend the preparation to the treatment of the condition, the intramuscular use of DEPO-NISOLONE is indicated as follows: 1. Endocrine Disorders: Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone acetate is the drug of choice; synthetic analogues may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance). Acute adrenocortical insufficiency (hydrocortisone or cortisone acetate is the drug of choice; mineralocorticoid supplementation may be necessary, particularly when synthetic analogues are used). Preoperatively and in the event of serious trauma or illness, in patients with known adrenal insufficiency or when adrenocortical reserve is doubtful. Congenital adrenal hyperplasia. Hypercalcaemia associated with cancer. Non-suppurative thyroiditis. 2. Rheumatic Disorders. As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Post-traumatic osteoarthritis. Epicondylitis. Synovitis of osteoarthritis. Acute non-specific tenosynovitis. Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy). Acute gouty arthritis. Psoriatic arthritis. Ankylosing spondylitis. Acute and subacute bursitis. 3. Collagen Diseases. During an exacerbation or as maintenance therapy in selected cases of: Systemic lupus erythematosus. Acute rheumatic carditis. Systemic dermatomyositis (polymyositis). 4. Dermatological Diseases. Pemphigus. Bullous dermatitis herpetiformis. Severe erythema multiforme (Stevens-Johnson Syndrome). Severe seborrhoeic dermatitis. Exfoliative dermatitis. Severe psoriasis. Mycosis fungoides. 5. Allergic States. Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in: Bronchial asthma. Drug hypersensitivity reactions. Contact dermatitis.Urticarial transfusion reactions. Atopic dermatitis. Acute non-infectious laryngeal oedema (adrenaline is the drug of first choice). Serum sickness. 6. Ophthalmic Diseases. Severe acute and chronic allergic and inflammatory processes involving the eye, such as: Herpes zoster ophthalmicus. Sympathetic ophthalmia. Iritis, iridocyclitis. Anterior segment inflammation. Chorioretinitis. Allergic conjunctivitis. Diffuse posterior uveitis. Allergic corneal marginal ulcers. Optic neuritis. Keratitis. 7. Gastrointestinal Diseases. To tide the patient over a critical period of the disease in: Ulcerative colitis (systemic therapy). Regional enteritis (systemic therapy). 8. Respiratory Diseases.Symptomatic sarcoidosis. Berylliosis. Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate anti-tuberculous chemotherapy. Aspiration pneumonitis. Loeffler's Syndrome not manageable by other means. 9. Haematological Disorders. Acquired (autoimmune) haemolytic anaemia. Erythroblastopenia (RBC anaemia). Secondary thrombocytopenia in adults. Congenital (erythroid) hypoplastic anaemia. 10. Neoplastic Diseases. For palliative management of: Leukaemias and lymphomas in adults. Acute leukaemia in childhood. 11. Oedematous States. To induce diuresis or remission of proteinuria in the nephrotic syndrome without uraemia of the idiopathic type or that due to lupus erythematosus. 12. Miscellaneous. Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate anti-tuberculous chemotherapy. Trichinosis with neurological or myocardial involvement. B. For Intra-Articular Or Soft Tissue Administration DEPO-NISOLONE is indicated as adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Synovitis of osteoarthritis. Epicondylitis. Rheumatoid arthritis. Acute non-specific tenosynovitis. Acute and subacute bursitis. Post-traumatic osteoarthritis. Acute gouty arthritis. C. For Intralesional Administration. DEPO-NISOLONE is indicated for intralesional use in the following conditions: Keloids.Discoid lupus erythematosus. Necrobiosis lipoidica diabeticorum. Alopecia areata. Localised hypertrophic, infiltrated inflammatory lesions of Licen Planus, psoriatic plaques, Granuloma Annulare and Lichen Simplex Chronicus (neurodermatitis). DEPO-NISOLONE may also be useful in cystic tumours of an aponeurosis or tendon (ganglia).

Source: ARTG

• Shelf lifetime is 3 Years
• Store below 30 degrees Celsius
• Do not Freeze

Source: ARTG

Non-composite pack

This medicine contains one component only.

Component

• Injection, suspension
• Intraarticular
• White to off white suspension when mixed

Source: ARTG

These medicine packs are available from a pharmacist and requires a prescription. It is Schedule 4: Prescription Only Medicine.?What is the medicines and poisons schedule?

All medicines and poisons in Australia are categorised by how they are made available to the public. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk. This system is called ‘scheduling’. You can read more about the scheduling of medicines as well as the different scheduling categories on our Scheduling of medicines and poisons information page.

• 1 mL X 1
• 1mL X 5

Source: ARTG

This medicine is not listed on the Pharmaceutical Benefits Scheme (PBS). Talk to your pharmacist about how much it will cost.

Source: PBS

For the active ingredient: methylprednisolone acetate

You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Source: AHT

If you experience a side effect from this medicine, tell your doctor or pharmacist. Or report it directly to the TGA (Therapeutic Goods Administration).

You can report side effects to your doctor, or directly at Report an adverse event or safety problem (Opens in new tab)

Source: ARTG

Healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.

Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions (Opens in new tab).