Estalis Continuous 50/250™
Active ingredients: Estradiol + norethisterone acetate
Consumer medicine information
Read the CMI leaflet (Opens in new tab) for facts you need to know before, during and after taking your medicine.
For more information about CMIs and how to read them, please visit How to read Consumer Medicine Information (CMI).
What this medicine is used for
For the short-term treatment of symptoms of oestrogen deficiency in menopausal women who have an intact uterus. For prevention of postmenopausal bone mineral density loss in women with an increased risk of future osteoporotic fractures who are intolerant of, or contraindicated for, other medicinal products approved for the prevention of bone mineral density loss. When prescribed solely for the prevention of postmenopausal bone mineral density loss, therapy should only be prescribed for women who are at high risk of future fracture and who are intolerant of, or contraindicated for non-oestrogen products approved for prevention of bone mineral density loss. Lifestyle modifications and the risk-benefit profile of Estalis Continous should be taken into careful consideration and discussed with the patient to allow the patient to make an informed decision prior to prescribing. Combination HRT should not be used in hysterectomised women because it is not needed in these women and it may increase the risk of breast cancer.
Source: ARTG
Storage conditions
- Shelf lifetime is 18 Months
- Store at 2 to 8 degrees Celsius
- Do not Freeze; Refrigerate
Source: ARTG
How to use this medicine
Non-composite pack
This medicine contains one component only.
Component
- Drug delivery system, transdermal
- Transdermal
- An off-white translucent patch with a removable pre-cut liner: 16cm2 round patch.
Source: ARTG
Do I need a prescription?
These medicine packs are available from a pharmacist and requires a prescription. It is Schedule 4: Prescription Only Medicine.
- 2 patches sample pack
- 8 patches
Source: ARTG
Is this medicine subsidised?
This medicine is not listed on the Pharmaceutical Benefits Scheme (PBS). Talk to your pharmacist about how much it will cost.
Source: PBS
Over 65?
For the active ingredient: Estradiol + norethisterone acetate
If you are over 65 years of age, there may be specific risks and recommendations for use of this medicine. Please discuss your individual circumstances with your pharmacist, doctor or health professional. For more information read our page on medication safety for older people.
Source: AHT
Pregnant or planning a pregnancy?
For the active ingredient: Estradiol + norethisterone acetate
You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.
Source: AHT
Reporting side effects
If you experience a side effect from this medicine, tell your doctor or pharmacist. Or report it directly to the TGA (Therapeutic Goods Administration).
You can report side effects to your doctor, or directly at Report an adverse event or safety problem (Opens in new tab)
Source: ARTG
Data sources
- Australian Health Thesaurus (AHT) (Opens in new tab) – Last updated on 3 August 2026
- Australian Medicines Terminology (AMT) (Opens in new tab) – Last updated on 3 August 2026
- Australian Register of Therapeutic Goods (ARTG) (Opens in new tab) – Last updated on 3 August 2026
- Pharmaceutical Benefits Scheme (PBS) (Opens in new tab) – Last updated on 3 August 2026
- Medicines Information Pty Ltd (Opens in new tab) – Last updated on 4 March 2026
Disclaimer
Healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.
Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions (Opens in new tab).
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